S47A2 Antibody

Product Specifications

Background

S47A2 belongs to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of the MATE transporter family located near each other on chromosome 17.

NCBI Gene ID

146802

Swiss Prot

Q86VL8

Accession Number

Q86VL8

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This S47A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-153 amino acids from the N-terminal region of human S47A2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

65 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SLC47A2

NCBI Official Name

Multidrug and toxin extrusion protein 2

NCBI Organism

Homo sapiens

Background Reference 01

Toyama, K., et al. Pharmacogenet. Genomics 20 (2) :135-138 (2010)

Background Reference 02

Kajiwara, M., et al. J. Hum. Genet. 54 (1) :40-46 (2009)

Background Reference 03

Ohta, K.Y., et al.Pharm Pharm Sci 12 (3) :388-396 (2009)

Other Product Names

Multidrug and toxin extrusion protein 2, MATE-2, hMATE-2, Kidney-specific H (+) /organic cation antiporter, Solute carrier family 47 member 2, SLC47A2, MATE2