What is the catalog number for S6K Antibody?

The catalog number for S6K Antibody is 61-628.

What sizes are available for S6K Antibody?

S6K Antibody is available in the following size(s): 400 µL.

Is S6K Antibody in stock?

S6K Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

S6K Antibody

Product Specifications

Background

RPS6KB1 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding the gene for RPS6KB1 and overexpression of this kinase are seen in some breast cancer cell lines.

NCBI Gene ID

6198

Swiss Prot

P23443

Accession Number

P23443

Host

Rabbit

Reactivity

Human

Immunogen

This S6K (RPS6KB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 405-434 amino acids from human S6K (RPS6KB1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Obesity, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rabbit, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

59 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

RPS6KB1

NCBI Official Name

Ribosomal protein S6 kinase beta-1

NCBI Organism

Homo sapiens

Background Reference 01

Adem, C., et al., Genes Chromosomes Cancer 41 (1) :1-11 (2004) .

Background Reference 02

Suzuki, Y., et al., Genome Res. 14 (9) :1711-1718 (2004) .

Background Reference 03

Gomez-Cambronero, J., et al., Leuk. Res. 28 (7) :755-762 (2004) .

Background Reference 04

Raught, B., et al., EMBO J. 23 (8) :1761-1769 (2004) .

Other Product Names

Ribosomal protein S6 kinase beta-1, S6K-beta-1, S6K1, 70 kDa ribosomal protein S6 kinase 1, P70S6K1, p70-S6K 1, Ribosomal protein S6 kinase I, Serine/threonine-protein kinase 14A, p70 ribosomal S6 kinase alpha, p70 S6 kinase alpha, p70 S6K-alpha, p70 S6KA, RPS6KB1, STK14A