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IMMT Antibody

Product Specifications

Background

Mitochondria are the center of cellular energy production and essential metabolic reactions. As double membrane-bound organelles, mitochondria from different species, tissues, and metabolic states are highly polymorphic in nature, yet exhibit common structural features. The ultrastructural variations in mitochondrial architecture occur mainly due to the differences in the amount and shape of cristae. Abundant cristae are found in mitochondria from tissues where energy demand is high. Analysis of the human heart mitochondrial proteome shows that mitofilin is one of the most abundant mitochondrial proteins. It appears to play an important role in the maintenance of cristae morphology.

NCBI Gene ID

10989

Swiss Prot

Q16891

Accession Number

Q16891

Host

Rabbit

Reactivity

Human

Immunogen

This IMMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 700-729 amino acids from the C-terminal region of human IMMT.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

84 kDa

Fragment

Rabbit Ig

Symbol

IMMT

NCBI Official Name

MICOS complex subunit MIC60

NCBI Organism

Homo sapiens

Background Reference 01

Bernert, G., et.al., Proteomics (12), 1752-1757 (2002)

Other Product Names

MICOS complex subunit MIC60, Cell proliferation-inducing gene 4/52 protein, Mitochondrial inner membrane protein, Mitofilin, p87/89, IMMT, HMP, MIC60, MINOS2

Tested Applications

WB, IHC-P, Flow

Protein ID

29427676

Physical Properties

Liquid

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