PRDX6 Antibody

Product Specifications

Background

PRDX6is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H (2) O (2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.

NCBI Gene ID

9588

Swiss Prot

P30041

Accession Number

P30041

Host

Rabbit

Reactivity

Human

Immunogen

This PRDX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-224 amino acids from the C-terminal region of human PRDX6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Monkey, Mouse, Pig, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

25 kDa

Fragment

Rabbit Ig

Symbol

PRDX6

NCBI Official Name

Peroxiredoxin-6

NCBI Organism

Homo sapiens

Background Reference 01

Sorokina, E.M., et.al., Am. J. Physiol. Lung Cell Mol. Physiol. 297 (5), L871-L880 (2009)

Background Reference 02

Manevich, Y., et.al., Arch. Biochem. Biophys. 485 (2), 139-149 (2009)

Other Product Names

Peroxiredoxin-6, 1-Cys peroxiredoxin, 1-Cys PRX, 24 kDa protein, Acidic calcium-independent phospholipase A2, aiPLA2, 311-, Antioxidant protein 2, Liver 2D page spot 40, Non-selenium glutathione peroxidase, NSGPx, Red blood cells page spot 12, PRDX6, AOP2, KIAA0106