CD49e Antibody
Product Specifications
Background
CD49e belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein is the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
NCBI Gene ID
3678
Swiss Prot
P08648
Accession Number
P08648
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This CD49e antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 796-824 amino acids from the C-terminal region of human CD49e.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=61-569
Calculated Molecular Weight
115 kDa
Fragment
Rabbit Ig
Symbol
ITGA5
NCBI Official Name
Integrin alpha-5
NCBI Organism
Homo sapiens
Background Reference 01
Boehmler, A.M., J. Immunol. 182 (11), 6789-6798 (2009)
Background Reference 02
Okazaki, T., Am. J. Pathol. 174 (6), 2378-2387 (2009)
Background Reference 03
Schornberg, K.L., Proc. Natl. Acad. Sci. U.S.A. 106 (19), 8003-8008 (2009)
Other Product Names
Integrin alpha-5, CD49 antigen-like family member E, Fibronectin receptor subunit alpha, Integrin alpha-F, VLA-5, CD49e, Integrin alpha-5 heavy chain, Integrin alpha-5 light chain, ITGA5, FNRA
Tested Applications
WB, Flow
Protein ID
23831237
Physical Properties
Liquid
Curated Selection
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