POLR1C Antibody
Product Specifications
Background
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft.
NCBI Gene ID
9533
Swiss Prot
O15160
Accession Number
O15160
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This POLR1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 319-346 amino acids from the C-terminal region of human POLR1C.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=61-539
Calculated Molecular Weight
39 kDa
Fragment
Rabbit Ig
Symbol
POLR1C
NCBI Official Name
DNA-directed RNA polymerases I and III subunit RPAC1
NCBI Organism
Homo sapiens
Background Reference 01
Rush, J., Nat. Biotechnol. 23 (1), 94-101 (2005)
Background Reference 02
Hirschler-Laszkiewicz, I., J. Biol. Chem. 278 (21), 18953-18959 (2003)
Background Reference 03
Dammann, R., Biochim. Biophys. Acta 1396 (2), 153-157 (1998)
Background Reference 04
Seither, P., Chromosoma 106 (4), 216-225 (1997)
Other Product Names
DNA-directed RNA polymerases I and III subunit RPAC1, DNA-directed RNA polymerase I subunit C, RNA polymerases I and III subunit AC1, AC40, DNA-directed RNA polymerases I and III 40 kDa polypeptide, RPA40, RPA39, RPC40, POLR1C, POLR1E
Tested Applications
WB, IHC-P
Physical Properties
Liquid
Curated Selection
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