IRF8 Antibody
Product Specifications
Background
Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.
NCBI Gene ID
3394
Swiss Prot
Q02556
Accession Number
Q02556
Host
Rabbit
Reactivity
Human
Immunogen
This IRF8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-269 amino acids from the Central region of human IRF8.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=61-533
Calculated Molecular Weight
48 kDa
Fragment
Rabbit Ig
Symbol
IRF8
NCBI Official Name
Interferon regulatory factor 8
NCBI Organism
Homo sapiens
Background Reference 01
McGough, J.M., Mol. Cancer Res. (12), 1841-1851 (2008)
Background Reference 02
Tshuikina, M., Exp. Hematol. 36 (12), 1673-1681 (2008)
Background Reference 03
Martinez, A., Am. J. Surg. Pathol. 32 (8), 1190-1200 (2008)
Other Product Names
Interferon regulatory factor 8, IRF-8, Interferon consensus sequence-binding protein, H-ICSBP, ICSBP, IRF8, ICSBP1
Tested Applications
WB, Flow
Protein ID
6016308
Physical Properties
Liquid
Curated Selection
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