EXOSC8 Antibody
Product Specifications
Background
EXOSC8 is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3'-untranslated regions. It is required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA and has a 3'-5' exonuclease activity.
NCBI Gene ID
11340
Swiss Prot
Q96B26
Accession Number
Q96B26
Host
Rabbit
Reactivity
Human
Immunogen
This EXOSC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-276 amino acids from the C-terminal region of human EXOSC8.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
30 kDa
Fragment
Rabbit Ig
Symbol
EXOSC8
NCBI Official Name
Exosome complex component RRP43
NCBI Organism
Homo sapiens
Background Reference 01
Raijmakers, R., J. Mol. Biol. 323 (4), 653-663 (2002)
Background Reference 02
Jiang, T., Proc. Natl. Acad. Sci. U.S.A. 99 (8), 5295-5300 (2002)
Background Reference 03
Raijmakers, R., J. Mol. Biol. 315 (4), 809-818 (2002)
Background Reference 04
Brouwer, R., J. Biol. Chem. 276 (9), 6177-6184 (2001)
Other Product Names
Exosome complex component RRP43, Exosome component 8, Opa-interacting protein 2, OIP-2, Ribosomal RNA-processing protein 43, p9, EXOSC8, OIP2, RRP43
Tested Applications
WB, IHC-P, Flow
Protein ID
21759409
Physical Properties
Liquid
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