Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

DCX Antibody

Product Specifications

Background

In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. It contains two doublecortin domains, which bind microtubules. In addition, this protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in the gene encoding DCX are a cause of X-linked lissencephaly.

NCBI Gene ID

1641

Swiss Prot

O43602

Accession Number

O43602

Host

Rabbit

Reactivity

Human

Immunogen

This DCX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-137 amino acids from human DCX.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=61-496

Calculated Molecular Weight

49 kDa

Fragment

Rabbit Ig

Symbol

DCX

NCBI Official Name

Neuronal migration protein doublecortin

NCBI Organism

Homo sapiens

Background Reference 01

Leger, P.L., Neurogenetics (2008)

Background Reference 02

Zhang, Y., Biochem. Biophys. Res. Commun. 363 (3), 694-700 (2007)

Other Product Names

Neuronal migration protein doublecortin, Doublin, Lissencephalin-X, Lis-X, DCX, DBCN, LISX

Tested Applications

WB, IHC-P

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

DUSP22 Rabbit pAb (APR27254N)
APR27254N-01 50 µL

DUSP22 Rabbit pAb (APR27254N)

Ask
View Details
DUSP22 Rabbit pAb (APR27254N)
APR27254N-02 100 µL

DUSP22 Rabbit pAb (APR27254N)

Ask
View Details
DUSP22 Rabbit pAb (APR27254N)
APR27254N-03 200 µL

DUSP22 Rabbit pAb (APR27254N)

Ask
View Details
Anti-TPSB2 Antibody (R1R45)
RHD38101 100 μg

Anti-TPSB2 Antibody (R1R45)

Ask
View Details
Rabbit Polyclonal DAPK3/ZIPK Antibody [Alexa Fluor 647]
NBP2-98766AF647 0.1 mL

Rabbit Polyclonal DAPK3/ZIPK Antibody [Alexa Fluor 647]

Ask
View Details