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ZIC3 Antibody

Product Specifications

Background

This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This nuclear protein probably functions as a transcription factor in early stages of left-right body axis formation. Mutations in this gene cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs.

NCBI Gene ID

7547

Swiss Prot

O60481

Accession Number

O60481

Host

Rabbit

Reactivity

Human

Immunogen

This ZIC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-267 amino acids from the Central region of human ZIC3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Neuroscience, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=61-491

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Symbol

ZIC3

NCBI Official Name

Zinc finger protein ZIC 3

NCBI Organism

Homo sapiens

Background Reference 01

Hatayama, M., et al. Hum. Mol. Genet. 17 (22) :3459-3473 (2008)

Background Reference 02

Zhu, L., et al. Hum. Mutat. 29 (1) :99-105 (2008)

Background Reference 03

Zhu, L., et al. Hum. Mol. Genet. 16 (14) :1649-1660 (2007)

Background Reference 04

Chhin, B., et al. Hum. Mutat. 28 (6) :563-570 (2007)

Other Product Names

Zinc finger protein ZIC 3, Zinc finger protein 203, Zinc finger protein of the cerebellum 3, ZIC3, ZNF203

Tested Applications

WB, IHC-P, Flow

Physical Properties

Liquid

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