CYP26A1 Antibody
Product Specifications
Background
CYP26A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues.
NCBI Gene ID
1592
Swiss Prot
O43174
Accession Number
O43174
Host
Rabbit
Reactivity
Human
Immunogen
This CYP26A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-147 amino acids from the Central region of human CYP26A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
56 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CYP26A1
NCBI Official Name
Cytochrome P450 26A1
NCBI Organism
Homo sapiens
Background Reference 01
Quere, R., Blood 109 (10), 4450-4460 (2007)
Background Reference 02
Lee, S.J., Pharmacogenet. Genomics 17 (3), 169-180 (2007)
Background Reference 03
Heise, R., J. Invest. Dermatol. 126 (11), 2473-2480 (2006)
Other Product Names
Cytochrome P450 26A1, 114--, Cytochrome P450 retinoic acid-inactivating 1, Cytochrome P450RAI, hP450RAI, Retinoic acid 4-hydroxylase, Retinoic acid-metabolizing cytochrome, CYP26A1, CYP26, P450RAI1
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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