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MCT1 Antibody

Product Specifications

Background

SLC16A1 is a monocarboxylate transporter (MCT1) that mediates the movement of lactate and pyruvate across cell membranes. Import and export of these substrates by tissues such as erythrocytes, muscle, intestine, and kidney are ascribed largely to the action of a proton-coupled MCT (Garcia et al., 1994 [PubMed 8124722]) .

NCBI Gene ID

6566

Swiss Prot

P53985

Accession Number

P53985

Host

Rabbit

Reactivity

Human

Immunogen

This MCT1 (SLC16A1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-228 amino acids from the Central region of human MCT1 (SLC16A1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

54 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SLC16A1

NCBI Official Name

Monocarboxylate transporter 1

NCBI Organism

Homo sapiens

Background Reference 01

Pinheiro, C., Virchows Arch. 452 (2), 139-146 (2008)

Background Reference 02

Otonkoski, T., Am. J. Hum. Genet. 81 (3), 467-474 (2007)

Background Reference 03

Martin-Venegas, R., J. Nutr. 137 (1), 49-54 (2007)

Other Product Names

Monocarboxylate transporter 1, MCT 1, Solute carrier family 16 member 1, SLC16A1, MCT1

Tested Applications

WB

Protein ID

313104214

Physical Properties

Liquid

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