Vimentin Antibody

Product Specifications

Background

Along with the microfilaments (actins) and microtubules (tubulins), the intermediate filaments represent a third class of well-characterized cytoskeletal elements. The subunits display a tissue-specific pattern of expression. Desmin (MIM 125660) is the subunit specific for muscle and vimentin the subunit specific for mesenchymal tissue.

NCBI Gene ID

7431

Swiss Prot

P08670

Accession Number

P08670

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Vimentin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-90 amino acids from human Vimentin.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Hamster, Monkey, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

54 kDa

Fragment

Rabbit Ig

Symbol

VIM

NCBI Official Name

Vimentin

NCBI Organism

Homo sapiens

Background Reference 01

References for protein:

Background Reference 02

Whipple, R.A., Cancer Res. 68 (14), 5678-5688 (2008)

Background Reference 03

Garcia-Verdugo, I., Biochemistry 47 (18), 5127-5138 (2008)

Background Reference 04

Merdes, A., J. Cell Biol. 115 (2), 397-410 (1991)

Other Product Names

Vimentin, VIM

Tested Applications

WB, IHC-P, IF

Protein ID

55977767

Physical Properties

Liquid

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