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AKR1B1 Antibody

Product Specifications

Background

AKR1B1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol.

NCBI Gene ID

231

Swiss Prot

P15121

Accession Number

P15121

Host

Rabbit

Reactivity

Human

Immunogen

This AKR1B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-135 amino acids from the Central region of human AKR1B1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

36 kDa

Fragment

Rabbit Ig

Symbol

AKR1B1

NCBI Official Name

Aldose reductase

NCBI Organism

Homo sapiens

Background Reference 01

Steuber, H., J. Mol. Biol. 379 (5), 991-1016 (2008)

Background Reference 02

Gleissner, C.A., Arterioscler. Thromb. Vasc. Biol. 28 (6), 1137-1143 (2008)

Background Reference 03

Grundmann, U., DNA Cell Biol. (3), 149-157 (1990)

Other Product Names

Aldose reductase, AR, Aldehyde reductase, Aldo-keto reductase family 1 member B1, AKR1B1, ALDR1

Tested Applications

WB, IHC-P, IF

Protein ID

113596

Physical Properties

Liquid

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