AKR1B1 Antibody
Product Specifications
Background
AKR1B1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol.
NCBI Gene ID
231
Swiss Prot
P15121
Accession Number
P15121
Host
Rabbit
Reactivity
Human
Immunogen
This AKR1B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-316 amino acids from the C-terminal region of human AKR1B1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
36 kDa
Fragment
Rabbit Ig
Symbol
AKR1B1
NCBI Official Name
Aldose reductase
NCBI Organism
Homo sapiens
Background Reference 01
Steuber, H., J. Mol. Biol. 379 (5), 991-1016 (2008)
Background Reference 02
Gleissner, C.A., Arterioscler. Thromb. Vasc. Biol. 28 (6), 1137-1143 (2008)
Background Reference 03
Grundmann, U., DNA Cell Biol. (3), 149-157 (1990)
Other Product Names
Aldose reductase, AR, Aldehyde reductase, Aldo-keto reductase family 1 member B1, AKR1B1, ALDR1
Tested Applications
WB, IHC-P, IF
Protein ID
113596
Physical Properties
Liquid
Frequently Asked Questions
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