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INDO Antibody

Product Specifications

Background

Gamma-interferon (IFNG; MIM 147570) has an antiproliferative effect on many tumor cells and inhibits intracellular pathogens such as Toxoplasma and Chlamydia, at least partly because of the induction of indoleamine 2,3-dioxygenase (INDO; EC 1.13.11.52) . This enzyme catalyzes the degradation of the essential amino acid L-tryptophan to N-formyl-kynurenine.[supplied by OMIM]

NCBI Gene ID

3620

Swiss Prot

P14902

Accession Number

P14902

Host

Rabbit

Reactivity

Human

Immunogen

This INDO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-403 amino acids from the C-terminal region of human INDO.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

45 kDa

Fragment

Rabbit Ig

Symbol

IDO1

NCBI Official Name

Indoleamine 2,3-dioxygenase 1

NCBI Organism

Homo sapiens

Background Reference 01

Maghzal, G.J., J. Biol. Chem. 283 (18), 12014-12025 (2008)

Background Reference 02

Chauhan, N., Biochemistry 47 (16), 4761-4769 (2008)

Background Reference 03

Scheler, M., Am. J. Pathol. 171 (6), 1936-1943 (2007)

Other Product Names

Indoleamine 2,3-dioxygenase 1, IDO-1, Indoleamine-pyrrole 2,3-dioxygenase, IDO1, IDO, INDO

Tested Applications

WB, IHC-P

Protein ID

123948

Physical Properties

Liquid

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