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Junctophilin 3 Antibody

Product Specifications

Background

Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Junctophilin 3 is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane.

NCBI Gene ID

57340

Swiss Prot

Q9ET77

Accession Number

Q9ET77

Host

Rabbit

Reactivity

Mouse

Immunogen

This Junctophilin 3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 549-578 amino acids from the Central region of human Junctophilin 3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein G column, followed by dialysis against PBS.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Human

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=61-445

Calculated Molecular Weight

81 kDa

Fragment

Rabbit Ig

Symbol

Jph3

NCBI Official Name

Junctophilin-3

NCBI Organism

Mus musculus

Background Reference 01

Kakizawa, S., EMBO J. 26 (7), 1924-1933 (2007)

Background Reference 02

Moriguchi, S., Proc. Natl. Acad. Sci. U.S.A. 103 (28), 10811-10816 (2006)

Background Reference 03

Nishi, M., Brain Res. Mol. Brain Res. 118 (1-2), 102-110 (2003)

Background Reference 04

Nishi, M., Biochem. Biophys. Res. Commun. 292 (2), 318-324 (2002)

Other Product Names

Junctophilin-3, JP-3, Junctophilin type 3, Jph3, Jp3

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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