Dtnbp1 Antibody

Product Specifications

Background

Dtnp1 may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC) . Mutations in this protein are associated with Hermansky-Pudlak syndrome type 7. This protein may also be associated with schizophrenia.

NCBI Gene ID

94245

Swiss Prot

Q91WZ8

Accession Number

Q91WZ8

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Dtnbp1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-325 amino acids from the C-terminal region of human Dtnbp1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

40 kDa

Fragment

Rabbit Ig

Symbol

Dtnbp1

NCBI Official Name

Dysbindin

NCBI Organism

Mus musculus

Background Reference 01

Benson M.A., J. Biol. Chem. 276:24232-24241 (2001) .

Background Reference 02

Li W., Nat. Genet. 35:84-89 (2003) .

Background Reference 03

Talbot K., Hum. Mol. Genet. 15:3041-3054 (2006) .

Other Product Names

Dysbindin, Biogenesis of lysosome-related organelles complex 1 subunit 8, BLOC-1 subunit 8, Dysbindin-1, Dystrobrevin-binding protein 1, Hermansky-Pudlak syndrome 7 protein homolog, HPS7 protein homolog, Dtnbp1, Bloc1s8, Sdy