Msx2 Antibody
Product Specifications
Background
This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.
NCBI Gene ID
4488
Swiss Prot
P35548
Accession Number
P35548
Host
Rabbit
Reactivity
Human
Immunogen
This Msx2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-222 amino acids from the C-terminal region of human Msx2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
29 kDa
Fragment
Rabbit Ig
Symbol
MSX2
NCBI Official Name
Homeobox protein MSX-2
NCBI Organism
Homo sapiens
Background Reference 01
Shao, J.S., Ann. N. Y. Acad. Sci. 1117, 40-50 (2007)
Background Reference 02
Han, J., Mech. Dev. 124 (9-10), 729-745 (2007)
Background Reference 03
Ghassibe, M., Eur. J. Pediatr. 165 (10), 734-735 (2006)
Other Product Names
Homeobox protein MSX-2, Homeobox protein Hox-8, MSX2, HOX8
Tested Applications
WB, IHC-P
Protein ID
311033429
Physical Properties
Liquid
Frequently Asked Questions
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