YY1 Antibody

Product Specifications

Background

YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.

NCBI Gene ID

7528

Swiss Prot

P25490

Accession Number

P25490

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This YY1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-104 amino acids from the N-terminal region of human YY1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

45 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

YY1

NCBI Official Name

Transcriptional repressor protein YY1

NCBI Organism

Homo sapiens

Background Reference 01

Sucharov, C.C., et al., J. Biol. Chem. 278 (33) :31233-31239 (2003) . Kurisaki, K., et al., Mol. Cell. Biol. 23 (13) :4494-4510 (2003) . Huang, N.E., et al., Biochem. Biophys. Res. Commun. 306 (1) :267-275 (2003) . Moriuchi, M., et al., J. Biol. Chem. 278 (15) :13003-13007 (2003) . Hiromura, M., et al., J. Biol. Chem. 278 (16) :14046-14052 (2003) .