NYREN18 Antibody

Product Specifications

Background

NYREN18 is a specific down-regulator of the NEDD8 conjugation system. It recruits NEDD8 and its conjugates to the proteasome for degradation. It also interacts with PSMD4/S5a, a member of the regulatory subunit of the 26S proteasome.

NCBI Gene ID

51667

Swiss Prot

Q9Y5A7

Accession Number

Q9Y5A7

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This NYREN18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-117 amino acids from the N-terminal region of human NYREN18.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

71 kDa

Fragment

Rabbit Ig

Symbol

NUB1

NCBI Official Name

NEDD8 ultimate buster 1

NCBI Organism

Homo sapiens

Background Reference 01

Tanaka, T., et al., J. Biol. Chem. 278 (35) :32905-32913 (2003) .

Background Reference 02

Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99 (26) :16899-16903 (2002) .

Background Reference 03

Kito, K., et al., J. Biol. Chem. 276 (23) :20603-20609 (2001) .

Background Reference 04

Kamitani, T., et al., J. Biol. Chem. 276 (49) :46655-46660 (2001) .

Other Product Names

NEDD8 ultimate buster 1, Negative regulator of ubiquitin-like proteins 1, Renal carcinoma antigen NY-REN-18, NUB1, NYREN18

Tested Applications

WB, IHC-P

Protein ID

37154888

Physical Properties

Liquid

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