ZMPSTE24 Antibody
Product Specifications
Background
ZMPSTE24 is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.
NCBI Gene ID
10269
Swiss Prot
O75844
Accession Number
O75844
Host
Rabbit
Reactivity
Human
Immunogen
This ZMPSTE24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 440-470 amino acids from the C-terminal region of human ZMPSTE24.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Cell Cycle, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=61-386
Calculated Molecular Weight
55 kDa
Fragment
Rabbit Ig
Symbol
ZMPSTE24
NCBI Official Name
CAAX prenyl protease 1 homolog
NCBI Organism
Homo sapiens
Background Reference 01
Freije, J.M., et al., Genomics 58 (3) :270-280 (1999) .
Background Reference 02
Kumagai, H., et al., Biochim. Biophys. Acta 1426 (3) :468-474 (1999) .
Background Reference 03
Tam, A., et al., J. Cell Biol. 142 (3) :635-649 (1998) .
Other Product Names
CAAX prenyl protease 1 homolog, Farnesylated proteins-converting enzyme 1, FACE-1, Prenyl protein-specific endoprotease 1, Zinc metalloproteinase Ste24 homolog, ZMPSTE24, FACE1, STE24
Tested Applications
WB, IHC-P
Physical Properties
Liquid
Curated Selection
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