ZMPSTE24 Antibody

Product Specifications

Background

ZMPSTE24 is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.

NCBI Gene ID

10269

Swiss Prot

O75844

Accession Number

O75844

Host

Rabbit

Reactivity

Human

Immunogen

This ZMPSTE24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 440-470 amino acids from the C-terminal region of human ZMPSTE24.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Cell Cycle, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

55 kDa

Fragment

Rabbit Ig

Symbol

ZMPSTE24

NCBI Official Name

CAAX prenyl protease 1 homolog

NCBI Organism

Homo sapiens

Background Reference 01

Freije, J.M., et al., Genomics 58 (3) :270-280 (1999) .

Background Reference 02

Kumagai, H., et al., Biochim. Biophys. Acta 1426 (3) :468-474 (1999) .

Background Reference 03

Tam, A., et al., J. Cell Biol. 142 (3) :635-649 (1998) .

Other Product Names

CAAX prenyl protease 1 homolog, Farnesylated proteins-converting enzyme 1, FACE-1, Prenyl protein-specific endoprotease 1, Zinc metalloproteinase Ste24 homolog, ZMPSTE24, FACE1, STE24