MGAT1 Antibody

Product Specifications

Background

There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. MGAT1 (UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I) is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis.

NCBI Gene ID

4245

Swiss Prot

P26572

Accession Number

P26572

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This MGAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-46 amino acids from the N-terminal region of human MGAT1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Symbol

MGAT1

NCBI Official Name

Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

NCBI Organism

Homo sapiens

Background Reference 01

Tan, J., et al., Eur. J. Biochem. 231 (2) :317-328 (1995) .

Background Reference 02

Kumar, R., et al., Glycobiology 2 (4) :383-393 (1992) .

Background Reference 03

Hull, E., et al., Biochem. Biophys. Res. Commun. 176 (2) :608-615 (1991) .

Background Reference 04

Kumar, R., et al., Proc. Natl. Acad. Sci. U.S.A. 87 (24) :9948-9952 (1990) .

Other Product Names

Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I, GNT-I, GlcNAc-T I, MGAT1, GGNT1, GLCT1, GLYT1, MGAT