AGL Antibody
Product Specifications
Background
AGL is a glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in the AGL gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing.
NCBI Gene ID
178
Swiss Prot
P35573
Accession Number
P35573
Host
Rabbit
Reactivity
Human
Immunogen
This AGL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1479-1510 amino acids from the C-terminal region of human AGL.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=61-376
Calculated Molecular Weight
175 kDa
Fragment
Rabbit Ig
Symbol
AGL
NCBI Official Name
Glycogen debranching enzyme
NCBI Organism
Homo sapiens
Background Reference 01
Horinishi, A., et al., J. Hum. Genet. 47 (2) :55-59 (2002) .
Background Reference 02
Bao, Y., et al., Genomics 38 (2) :155-165 (1996) .
Background Reference 03
Yang, B.Z., et al., J. Biol. Chem. 267 (13) :9294-9299 (1992) .
Background Reference 04
Yang-Feng, T.L., et al., Genomics 13 (4) :931-934 (1992) .
Other Product Names
Glycogen debranching enzyme, Glycogen debrancher, 4-alpha-glucanotransferase, Oligo-1,4-1,4-glucantransferase, Amylo-alpha-1,6-glucosidase, Amylo-1,6-glucosidase, Dextrin 6-alpha-D-glucosidase, AGL, GDE
Tested Applications
WB, IF
Protein ID
116242491
Physical Properties
Liquid
Curated Selection
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