AGL Antibody

Product Specifications

Background

AGL is a glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in the AGL gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing.

NCBI Gene ID

178

Swiss Prot

P35573

Accession Number

P35573

Host

Rabbit

Reactivity

Human

Immunogen

This AGL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1479-1510 amino acids from the C-terminal region of human AGL.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

175 kDa

Fragment

Rabbit Ig

Symbol

AGL

NCBI Official Name

Glycogen debranching enzyme

NCBI Organism

Homo sapiens

Background Reference 01

Horinishi, A., et al., J. Hum. Genet. 47 (2) :55-59 (2002) .

Background Reference 02

Bao, Y., et al., Genomics 38 (2) :155-165 (1996) .

Background Reference 03

Yang, B.Z., et al., J. Biol. Chem. 267 (13) :9294-9299 (1992) .

Background Reference 04

Yang-Feng, T.L., et al., Genomics 13 (4) :931-934 (1992) .

Other Product Names

Glycogen debranching enzyme, Glycogen debrancher, 4-alpha-glucanotransferase, Oligo-1,4-1,4-glucantransferase, Amylo-alpha-1,6-glucosidase, Amylo-1,6-glucosidase, Dextrin 6-alpha-D-glucosidase, AGL, GDE