Methionine Aminopeptidase 2 Antibody

Product Specifications

Background

The ADP-ribosylation factor (Arf) family are highly conserved members of the Ras superfamily of regulatory GTP-binding proteins. Arf proteins participate in routing of intracellular proteins to and within the Golgi complex. Cellular functions include maintenance of organelle integrity, coat protein assembly, as an activator of phospholipase D. The Arf family is divided functionally into the Arf and the Arf-like (Arl) proteins. The ARF proteins are categorized as class I (ARF1, ARF2, and ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members of each class share a common gene organization.

NCBI Gene ID

10988

Swiss Prot

P50579

Accession Number

P50579

Host

Rabbit

Reactivity

Human

Immunogen

This Methionine Aminopeptidase 2 (METAP2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 437-467 amino acids from the C-terminal region of human Methionine Aminopeptidase 2 (METAP2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

53 kDa

Fragment

Rabbit Ig

Symbol

METAP2

NCBI Official Name

Methionine aminopeptidase 2 {ECO:0000255|HAMAP-Rule:MF_03175}

NCBI Organism

Homo sapiens

Background Reference 01

Wang, J., et al., Biochemistry 42 (17) :5035-5042 (2003) .

Background Reference 02

Datta, R., et al., Exp. Cell Res. 283 (2) :237-246 (2003) .

Background Reference 03

Endo, H., et al., J. Biol. Chem. 277 (29) :26396-26402 (2002) .

Background Reference 04

Kanno, T., et al., Lab. Invest. 82 (7) :893-901 (2002) .

Other Product Names

Methionine aminopeptidase 2 {ECO:0000255|HAMAP-Rule:MF_03175}, MAP 2 {ECO:0000255|HAMAP-Rule:MF_03175}, MetAP 2 {ECO:0000255|HAMAP-Rule:MF_03175}, 341118 {ECO:0000255|HAMAP-Rule:MF_03175}, Initiation factor 2-associated 67 kDa glycoprotein {ECO:0000255|HAMAP-Rule:MF_03175}, p67 {ECO:0000255|HAMAP-Rule:MF_03175}, p67eIF2 {ECO:0000255|HAMAP-Rule:MF_03175}, Peptidase M {ECO:0000255|HAMAP-Rule:MF_03175}, METAP2 {ECO:0000255|HAMAP-Rule:MF_03175}