PCSK1 Antibody

Product Specifications

Background

Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin.

NCBI Gene ID

5122

Swiss Prot

P29120

Accession Number

P29120

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This PCSK1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 682-715 amino acids from human PCSK1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Obesity, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

84 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:2000

Symbol

PCSK1

NCBI Official Name

Neuroendocrine convertase 1

NCBI Organism

Homo sapiens

Background Reference 01

Creemers J.W.M., et al.FEBS Lett. 300:82-88 (1992) .

Background Reference 02

Seidah N.G., et al.DNA Cell Biol. 11:283-289 (1992) .

Background Reference 03

Ohagi S., et al.Diabetes 45:897-901 (1996) .

Background Reference 04

Ota T., et al.Nat. Genet. 36:40-45 (2004) .

Other Product Names

Neuroendocrine convertase 1, NEC 1, 3.4.21.93, Prohormone convertase 1, Proprotein convertase 1, PC1, PCSK1, NEC1

Tested Applications

Protein ID

116242674

Physical Properties

Liquid

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