NaK ATPase Antibody

Product Specifications

Background

This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.

NCBI Gene ID

476

Swiss Prot

P05023

Accession Number

P05023

Host

Rabbit

Reactivity

Human

Immunogen

This NaK ATPase antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 12-46 amino acids from human NaK ATPase.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

113 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:2000

Symbol

ATP1A1

NCBI Official Name

Sodium/potassium-transporting ATPase subunit alpha-1

NCBI Organism

Homo sapiens

Background Reference 01

Kawakami K., et al.J. Biochem. 100:389-397 (1986) .

Background Reference 02

Ruiz A., et al.Gene 155:179-184 (1995) .

Background Reference 03

Ota T., et al.Nat. Genet. 36:40-45 (2004) .

Background Reference 04

Gregory S.G., et al.Nature 441:315-321 (2006) .

Other Product Names

Sodium/potassium-transporting ATPase subunit alpha-1, Na (+) /K (+) ATPase alpha-1 subunit, 3.6.3.9, Sodium pump subunit alpha-1, ATP1A1

Tested Applications

Protein ID

114374

Physical Properties

Liquid

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