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DNM2 Antibody

Product Specifications

Background

Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity) . Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis.

NCBI Gene ID

1785

Swiss Prot

P50570

Accession Number

P50570

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This DNM2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 213-247 amino acids from human DNM2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

98 kDa

Fragment

Rabbit Ig

Symbol

DNM2

NCBI Official Name

Dynamin-2

NCBI Organism

Homo sapiens

Background Reference 01

Diatloff-Zito C., et al.Gene 163:301-306 (1995) .

Background Reference 02

Ota T., et al.Nat. Genet. 36:40-45 (2004) .

Background Reference 03

Grimwood J., et al.Nature 428:529-535 (2004) .

Background Reference 04

Okamoto P.M., et al.J. Biol. Chem. 276:48458-48465 (2001) .

Other Product Names

Dynamin-2, 3.6.5.5, DNM2, DYN2

Tested Applications

WB, Flow

Protein ID

47117856

Physical Properties

Liquid

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