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CHRM3 Antibody

Product Specifications

Background

The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

NCBI Gene ID

1131

Swiss Prot

P20309

Accession Number

P20309

Host

Rabbit

Reactivity

Human

Immunogen

This CHRM3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 233-264 amino acids from the Central region of human CHRM3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse, Pig, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

66 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:16000

Symbol

CHRM3

NCBI Official Name

Muscarinic acetylcholine receptor M3

NCBI Organism

Homo sapiens

Background Reference 01

Peralta E.G., et al.EMBO J. 6:3923-3929 (1987) .

Background Reference 02

Bonner T.I., et al.Neuron 1:403-410 (1988) .

Background Reference 03

Kitano T., et al.Mol. Biol. Evol. 21:936-944 (2004) .

Background Reference 04

Puhl H.L. III, et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.

Other Product Names

Muscarinic acetylcholine receptor M3, CHRM3

Tested Applications

WB

Protein ID

113125

Physical Properties

Liquid

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