NT5M Antibody
Product Specifications
Background
Dephosphorylates specifically the 5' and 2' (3') - phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP.
NCBI Gene ID
56953
Swiss Prot
Q9NPB1
Accession Number
Q9NPB1
Host
Rabbit
Reactivity
Human
Immunogen
This NT5M antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 59-90 amino acids from the Central region of human NT5M.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
26 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:2000
Symbol
NT5M
NCBI Official Name
5' (3') -deoxyribonucleotidase, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Rampazzo C., et al.Proc. Natl. Acad. Sci. U.S.A. 97:8239-8244 (2000) .
Background Reference 02
Rinaldo-Matthis A., et al.Nat. Struct. Biol. 9:779-787 (2002) .
Other Product Names
5' (3') -deoxyribonucleotidase, mitochondrial, 5',3'-nucleotidase, mitochondrial, 3.1.3.-, Deoxy-5'-nucleotidase 2, dNT-2, NT5M, DNT2
Tested Applications
WB
Protein ID
38258255
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
