Vinculin
Product Specifications
Background
Actin filament (F-actin) -binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell- surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion (By similarity) .
NCBI Gene ID
22330
Swiss Prot
Q64727
Accession Number
Q64727
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 634-668 amino acids from mouse.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
117 kDa
Fragment
Rabbit Ig
Symbol
Vcl
NCBI Official Name
Vinculin
NCBI Organism
Mus musculus
Background Reference 01
Coll J.-L., et al.Proc. Natl. Acad. Sci. U.S.A. 92:9161-9165 (1995) .
Background Reference 02
Alatortsev V.E., et al.FEBS Lett. 413:197-201 (1997) .
Background Reference 03
Carninci P., et al.Science 309:1559-1563 (2005) .
Background Reference 04
Lubec G., et al.Submitted (JAN-2009) to UniProtKB.
Other Product Names
Vinculin, Metavinculin, Vcl
Tested Applications
WB, Flow
Physical Properties
Liquid
Frequently Asked Questions
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