What is the catalog number for Profilin-1 Antibody?

The catalog number for Profilin-1 Antibody is 61-323.

What sizes are available for Profilin-1 Antibody?

Profilin-1 Antibody is available in the following size(s): 200 µL.

Is Profilin-1 Antibody in stock?

Profilin-1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Profilin-1 Antibody

Product Specifications

Background

Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.

NCBI Gene ID

5216

Swiss Prot

P07737

Accession Number

P07737

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This Profilin-1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 108-140 amino acids from the human region of human Profilin-1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

15 kDa

Fragment

Rabbit Ig

Symbol

PFN1

NCBI Official Name

Profilin-1

NCBI Organism

Homo sapiens

Background Reference 01

Kwiatkowski D.J., et al.J. Biol. Chem. 263:5910-5915 (1988) .

Background Reference 02

Li J., et al.Mol. Cell. Proteomics 9:2517-2528 (2010) .

Background Reference 03

Kalnine N., et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.

Background Reference 04

Ota T., et al.Nat. Genet. 36:40-45 (2004) .

Other Product Names

Profilin-1, Epididymis tissue protein Li 184a, Profilin I, PFN1

Tested Applications

WB, Flow

Protein ID

130979

Physical Properties

Liquid

Frequently Asked Questions

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