SPTLC3 Antibody

Product Specifications

Background

Serine palmitoyltransferase (SPT) . The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC3-SPTSSA isozyme uses both C14-CoA and C16-CoA as substrates, while the SPTLC1-SPTLC3-SPTSSB has the ability to use a broader range of acyl-CoAs without apparent preference.

NCBI Gene ID

55304

Swiss Prot

Q9NUV7

Accession Number

Q9NUV7

Host

Rabbit

Reactivity

Human

Immunogen

This SPTLC3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 503-545 amino acids from human SPTLC3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

62 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:2000

Symbol

SPTLC3

NCBI Official Name

Serine palmitoyltransferase 3

NCBI Organism

Homo sapiens

Background Reference 01

Hornemann T., et al.J. Biol. Chem. 281:37275-37281 (2006) .

Background Reference 02

Ota T., et al.Nat. Genet. 36:40-45 (2004) .

Background Reference 03

Deloukas P., et al.Nature 414:865-871 (2001) .

Background Reference 04

Han G., et al.Proc. Natl. Acad. Sci. U.S.A. 106:8186-8191 (2009) .

Other Product Names

Serine palmitoyltransferase 3, 2.3.1.50, Long chain base biosynthesis protein 2b, LCB2b, Long chain base biosynthesis protein 3, LCB 3, Serine-palmitoyl-CoA transferase 3, SPT 3, SPTLC3, C20orf38, SPTLC2L