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GALC Antibody

Product Specifications

Background

Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon.

NCBI Gene ID

2581

Swiss Prot

P54803

Accession Number

P54803

Host

Rabbit

Reactivity

Human

Immunogen

This GALC antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 26-56 amino acids from human GALC.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=61-308

Calculated Molecular Weight

77 kDa

Fragment

Rabbit Ig

Symbol

GALC

NCBI Official Name

Galactocerebrosidase

NCBI Organism

Homo sapiens

Background Reference 01

Luzi P., et al.Genomics 26:407-409 (1995) .

Background Reference 02

Sakai N., et al.Biochim. Biophys. Acta 1395:62-67 (1998) .

Background Reference 03

Ota T., et al.Nat. Genet. 36:40-45 (2004) .

Background Reference 04

Heilig R., et al.Nature 421:601-607 (2003) .

Other Product Names

Galactocerebrosidase, GALCERase, 3.2.1.46, Galactocerebroside beta-galactosidase, Galactosylceramidase, Galactosylceramide beta-galactosidase, GALC

Tested Applications

WB, Flow

Protein ID

229462868

Physical Properties

Liquid

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