What is the catalog number for MLL3 Antibody?

The catalog number for MLL3 Antibody is 61-300.

What sizes are available for MLL3 Antibody?

MLL3 Antibody is available in the following size(s): 200 µL.

Is MLL3 Antibody in stock?

MLL3 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

MLL3 Antibody

Product Specifications

Background

Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.

NCBI Gene ID

58508

Swiss Prot

Q8NEZ4

Accession Number

Q8NEZ4

Host

Rabbit

Reactivity

Human

Immunogen

This MLL3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1142-1175 amino acids from the N-terminal region of human MLL3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

541 kDa

Fragment

Rabbit Ig

Applications Notes

For IHC-P starting dilution is: 1:25

Symbol

KMT2C

NCBI Official Name

Histone-lysine N-methyltransferase 2C

NCBI Organism

Homo sapiens

Background Reference 01

Ruault M., et al.Gene 284:73-81 (2002) .

Background Reference 02

Tan Y.C., et al.Cancer Detect. Prev. 25:454-469 (2001) .

Background Reference 03

Hillier L.W., et al.Nature 424:157-164 (2003) .

Background Reference 04

Nagase T., et al.DNA Res. 7:143-150 (2000) .

Other Product Names

Histone-lysine N-methyltransferase 2C, Lysine N-methyltransferase 2C, 2.1.1.43, Homologous to ALR protein, Myeloid/lymphoid or mixed-lineage leukemia protein 3, KMT2C, HALR, KIAA1506, MLL3