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NT5C Antibody

Product Specifications

Background

Dephosphorylates the 5' and 2' (3') -phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, intermediate activity towards dGMP, and low activity towards dCMP and dAMP.

NCBI Gene ID

30833

Swiss Prot

Q8TCD5

Accession Number

Q8TCD5

Host

Rabbit

Reactivity

Human

Immunogen

This NT5C antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 27-60 amino acids from human NT5C.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

23 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:2000

Symbol

NT5C

NCBI Official Name

5' (3') -deoxyribonucleotidase, cytosolic type

NCBI Organism

Homo sapiens

Background Reference 01

Rampazzo C., et al.J. Biol. Chem. 275:5409-5415 (2000) .

Background Reference 02

Ota T., et al.Nat. Genet. 36:40-45 (2004) .

Background Reference 03

Zody M.C., et al.Nature 440:1045-1049 (2006) .

Background Reference 04

Rampazzo C., et al.Gene 294:109-117 (2002) .

Other Product Names

5' (3') -deoxyribonucleotidase, cytosolic type, 3.1.3.-, Cytosolic 5',3'-pyrimidine nucleotidase, Deoxy-5'-nucleotidase 1, dNT-1, NT5C, DNT1, UMPH2

Tested Applications

WB

Protein ID

38258193

Physical Properties

Liquid

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