PRTN3 Antibody

Product Specifications

Background

Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.

NCBI Gene ID

5657

Swiss Prot

P24158

Accession Number

P24158

Host

Rabbit

Reactivity

Human

Immunogen

This PRTN3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 88-118 amino acids from the C-terminal region of human PRTN3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

28 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:2000

Symbol

PRTN3

NCBI Official Name

Myeloblastin

NCBI Organism

Homo sapiens

Background Reference 01

Labbaye C., et al.Proc. Natl. Acad. Sci. U.S.A. 88:9253-9256 (1991) .

Background Reference 02

Grimwood J., et al.Nature 428:529-535 (2004) .

Background Reference 03

Mural R.J., et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

Background Reference 04

Zimmer M., et al.Proc. Natl. Acad. Sci. U.S.A. 89:8215-8219 (1992) .

Other Product Names

Myeloblastin, 3.4.21.76, AGP7, C-ANCA antigen, Leukocyte proteinase 3, PR-3, PR3, Neutrophil proteinase 4, NP-4, P29, Wegener autoantigen, PRTN3, MBN

Tested Applications

Protein ID

6174926

Physical Properties

Liquid

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