SLC6A19 Antibody

Product Specifications

Background

Transporter that mediates epithelial resorption of neutral amino acids across the apical membrane of epithelial cells in the kidney and intestine. It appears that leucine is the preferred substrate, but all large neutral non-aromatic L-amino acids bind to this transporter. Uptake of leucine is sodium- dependent. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent (By similarity) .

NCBI Gene ID

340024

Swiss Prot

Q695T7

Accession Number

Q695T7

Host

Rabbit

Reactivity

Human

Immunogen

This SLC6A19 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 544-575 amino acids from human SLC6A19.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

71 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:2000

Symbol

SLC6A19

NCBI Official Name

Sodium-dependent neutral amino acid transporter B (0) AT1

NCBI Organism

Homo sapiens

Background Reference 01

Kleta R., et al.Nat. Genet. 36:999-1002 (2004) .

Background Reference 02

Seow H.F., et al.Nat. Genet. 36:1003-1007 (2004) .

Background Reference 03

Ota T., et al.Nat. Genet. 36:40-45 (2004) .

Background Reference 04

Mural R.J., et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

Other Product Names

Sodium-dependent neutral amino acid transporter B (0) AT1, Solute carrier family 6 member 19, System B (0) neutral amino acid transporter AT1, SLC6A19, B0AT1