GC Antibody

Product Specifications

Background

Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.

NCBI Gene ID

2638

Swiss Prot

P02774

Accession Number

P02774

Host

Rabbit

Reactivity

Human

Immunogen

This GC antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 442-473 amino acids from human GC.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

53 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:2000

Symbol

NCBI Official Name

Vitamin D-binding protein

NCBI Organism

Homo sapiens

Background Reference 01

Cooke N.E., et al.J. Clin. Invest. 76:2420-2424 (1985) .

Background Reference 02

Yang F., et al.Proc. Natl. Acad. Sci. U.S.A. 82:7994-7998 (1985) .

Background Reference 03

Braun A., et al.Biochim. Biophys. Acta 1216:385-394 (1993) .

Background Reference 04

Witke W.F., et al.Genomics 16:751-754 (1993) .

Other Product Names

Vitamin D-binding protein, DBP, VDB, Gc-globulin, Group-specific component, GC

Tested Applications

Protein ID

139641

Physical Properties

Liquid

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