MRI1 Antibody

Product Specifications

Background

Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) . Independently from catalytic activity, promotes cell invasion in response to constitutive RhoA activation by promoting FAK tyrosine phosphorylation and stress fiber turnover.

NCBI Gene ID

84245

Swiss Prot

Q9BV20

Accession Number

Q9BV20

Host

Rabbit

Reactivity

Human

Immunogen

This MRI1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 108-141 amino acids from the Central region of human MRI1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

39 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:8000

Symbol

MRI1

NCBI Official Name

Methylthioribose-1-phosphate isomerase {ECO:0000255|HAMAP-Rule:MF_03119}

NCBI Organism

Homo sapiens

Background Reference 01

Clark H.F., et al.Genome Res. 13:2265-2270 (2003) .

Background Reference 02

Bechtel S., et al.BMC Genomics 8:399-399 (2007) .

Background Reference 03

Mural R.J., et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

Background Reference 04

Kabuyama Y., et al.Mol. Cell. Proteomics 8:2308-2320 (2009) .

Other Product Names

Methylthioribose-1-phosphate isomerase {ECO:0000255|HAMAP-Rule:MF_03119}, M1Pi {ECO:0000255|HAMAP-Rule:MF_03119}, MTR-1-P isomerase {ECO:0000255|HAMAP-Rule:MF_03119}, 5.3.1.23 {ECO:0000255|HAMAP-Rule:MF_03119}, Mediator of RhoA-dependent invasion, S-methyl-5-thioribose-1-phosphate isomerase {ECO:0000255|HAMAP-Rule:MF_03119}, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein {ECO:0000255|HAMAP-Rule:MF_03119}, MRI1 {ECO:0000255|HAMAP-Rule:MF_03119}, MRDI