THRA Antibody

Product Specifications

Background

Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.

NCBI Gene ID

7067

Swiss Prot

P10827

Accession Number

P10827

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This THRA antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 107-139 amino acids from human THRA.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Chicken, Pig, Sheep

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

55 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:2000

Symbol

THRA

NCBI Official Name

Thyroid hormone receptor alpha

NCBI Organism

Homo sapiens

Background Reference 01

Laudet V., et al.Nucleic Acids Res. 19:1105-1112 (1991) .

Background Reference 02

Miyajima N., et al.Cell 57:31-39 (1989) .

Background Reference 03

Nakai A., et al.Proc. Natl. Acad. Sci. U.S.A. 85:2781-2785 (1988) .

Background Reference 04

Pfahl M., et al.Nucleic Acids Res. 15:9613-9613 (1987) .

Other Product Names

Thyroid hormone receptor alpha, Nuclear receptor subfamily 1 group A member 1, V-erbA-related protein 7, EAR-7, c-erbA-1, c-erbA-alpha, THRA, EAR7, ERBA1, NR1A1, THRA1, THRA2