MTUS1 Antibody

Product Specifications

Background

Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth.

NCBI Gene ID

57509

Swiss Prot

Q9ULD2

Accession Number

Q9ULD2

Host

Rabbit

Reactivity

Human

Immunogen

This MTUS1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 183-226 amino acids from human MTUS1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

141 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:2000

Symbol

MTUS1

NCBI Official Name

Microtubule-associated tumor suppressor 1

NCBI Organism

Homo sapiens

Background Reference 01

Kinjo T., et al.J. Hum. Genet. 45:12-17 (2000) .

Background Reference 02

Seibold S., et al.FASEB J. 17:1180-1182 (2003) .

Background Reference 03

Nouet S., et al.J. Biol. Chem. 279:28989-28997 (2004) .

Background Reference 04

Ota T., et al.Nat. Genet. 36:40-45 (2004) .

Other Product Names

Microtubule-associated tumor suppressor 1, AT2 receptor-binding protein, Angiotensin-II type 2 receptor-interacting protein, Mitochondrial tumor suppressor 1, MTUS1, ATBP, ATIP, GK1, KIAA1288, MTSG1