MTUS1 Antibody
Product Specifications
Background
Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth.
NCBI Gene ID
57509
Swiss Prot
Q9ULD2
Accession Number
Q9ULD2
Host
Rabbit
Reactivity
Human
Immunogen
This MTUS1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 983-1017 amino acids from human MTUS1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
141 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:2000
Symbol
MTUS1
NCBI Official Name
Microtubule-associated tumor suppressor 1
NCBI Organism
Homo sapiens
Background Reference 01
Kinjo T., et al.J. Hum. Genet. 45:12-17 (2000) .
Background Reference 02
Seibold S., et al.FASEB J. 17:1180-1182 (2003) .
Background Reference 03
Nouet S., et al.J. Biol. Chem. 279:28989-28997 (2004) .
Background Reference 04
Ota T., et al.Nat. Genet. 36:40-45 (2004) .
Other Product Names
Microtubule-associated tumor suppressor 1, AT2 receptor-binding protein, Angiotensin-II type 2 receptor-interacting protein, Mitochondrial tumor suppressor 1, MTUS1, ATBP, ATIP, GK1, KIAA1288, MTSG1
Tested Applications
WB
Protein ID
158706128
Physical Properties
Liquid
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