AKR7A3 Antibody

Product Specifications

Background

Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.

NCBI Gene ID

22977

Swiss Prot

O95154

Accession Number

O95154

Host

Rabbit

Reactivity

Human

Immunogen

This AKR7A3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 33-64 amino acids from the human region of human AKR7A3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

37 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:2000

Symbol

AKR7A3

NCBI Official Name

Aflatoxin B1 aldehyde reductase member 3

NCBI Organism

Homo sapiens

Background Reference 01

Knight L.P., et al.Carcinogenesis 20:1215-1223 (1999) .

Background Reference 02

Praml C., et al.Oncogene 22:4765-4773 (2003) .

Background Reference 03

Gregory S.G., et al.Nature 441:315-321 (2006) .

Background Reference 04

Bodreddigari S., et al.Chem. Res. Toxicol. 21:1134-1142 (2008) .

Other Product Names

Aflatoxin B1 aldehyde reductase member 3, 1.-.-.-, AFB1 aldehyde reductase 2, AFB1-AR 2, AKR7A3, AFAR2

Tested Applications

Physical Properties

Liquid

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