LLGL1 Antibody

Product Specifications

Background

LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17.

NCBI Gene ID

3996

Swiss Prot

Q15334

Accession Number

Q15334

Host

Rabbit

Reactivity

Human

Immunogen

This LLGL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-205 amino acids from the N-terminal region of human LLGL1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

115 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

LLGL1

NCBI Official Name

Lethal (2) giant larvae protein homolog 1

NCBI Organism

Homo sapiens

Background Reference 01

Schimanski, C.C., et al., Oncogene 24 (19) :3100-3109 (2005) . Grifoni, D., et al., Oncogene 23 (53) :8688-8694 (2004) . Katoh, M., et al., Int. J. Oncol. 24 (3) :737-742 (2004) . Bi, W., et al., Genome Res. 12 (5) :713-728 (2002) . Ludford-Menting, M.J., et al., J. Biol. Chem. 277 (6) :4477-4484 (2002) .