PF4 Antibody

Product Specifications

Background

Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.

NCBI Gene ID

5196

Swiss Prot

P02776

Accession Number

P02776

Host

Rabbit

Reactivity

Human

Immunogen

This PF4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 28-59 amino acids from human PF4.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

11 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:2000

Symbol

PF4

NCBI Official Name

Platelet factor 4

NCBI Organism

Homo sapiens

Background Reference 01

Poncz M., et al.Blood 69:219-223 (1987) .

Background Reference 02

Eisman R., et al.Blood 76:336-344 (1990) .

Background Reference 03

Zhang C., et al.Blood 98:610-617 (2001) .

Background Reference 04

Ebert L., et al.Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.

Other Product Names

Platelet factor 4, PF-4, C-X-C motif chemokine 4, Iroplact, Oncostatin-A, Platelet factor 4, short form, PF4, CXCL4, SCYB4

Tested Applications

Protein ID

130304

Physical Properties

Liquid

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