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NT5M Antibody

Product Specifications

Background

Dephosphorylates specifically the 5' and 2' (3') - phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP.

NCBI Gene ID

56953

Swiss Prot

Q9NPB1

Accession Number

Q9NPB1

Host

Rabbit

Reactivity

Human

Immunogen

This NT5M antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 195-226 amino acids from human NT5M.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

26 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:2000

Symbol

NT5M

NCBI Official Name

5' (3') -deoxyribonucleotidase, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Rampazzo C., et al.Proc. Natl. Acad. Sci. U.S.A. 97:8239-8244 (2000) .

Background Reference 02

Rinaldo-Matthis A., et al.Nat. Struct. Biol. 9:779-787 (2002) .

Other Product Names

5' (3') -deoxyribonucleotidase, mitochondrial, 5',3'-nucleotidase, mitochondrial, 3.1.3.-, Deoxy-5'-nucleotidase 2, dNT-2, NT5M, DNT2

Tested Applications

WB

Protein ID

38258255

Physical Properties

Liquid

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