IGFBP5 Antibody

Product Specifications

Background

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

NCBI Gene ID

3488

Swiss Prot

P24593

Accession Number

P24593

Host

Rabbit

Reactivity

Human

Immunogen

This IGFBP5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 87-121 amino acids from the Central region of human IGFBP5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

31 kDa

Fragment

IgG3

Applications Notes

For WB starting dilution is: 1:2000

Symbol

IGFBP5

NCBI Official Name

Insulin-like growth factor-binding protein 5

NCBI Organism

Homo sapiens

Background Reference 01

Kiefer M.C., et al.Biochem. Biophys. Res. Commun. 176:219-225 (1991) .

Background Reference 02

Shimasaki S., et al.J. Biol. Chem. 266:10646-10653 (1991) .

Background Reference 03

Allander S.V., et al.J. Biol. Chem. 269:10891-10898 (1994) .

Background Reference 04

Yu W., et al.Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.

Other Product Names

Insulin-like growth factor-binding protein 5, IBP-5, IGF-binding protein 5, IGFBP-5, IGFBP5, IBP5

Tested Applications

Protein ID

124069

Physical Properties

Liquid

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