HEXB Antibody

Product Specifications

Background

Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues.

NCBI Gene ID

3074

Swiss Prot

P07686

Accession Number

P07686

Host

Rabbit

Reactivity

Human

Immunogen

This HEXB antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 170-203 amino acids from the Central region of human HEXB.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

63 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:2000

Symbol

HEXB

NCBI Official Name

Beta-hexosaminidase subunit beta

NCBI Organism

Homo sapiens

Background Reference 01

Korneluk R.G., et al.J. Biol. Chem. 261:8407-8413 (1986) .

Background Reference 02

Neote K., et al.Genomics 3:279-286 (1988) .

Background Reference 03

Proia R.L., et al.Proc. Natl. Acad. Sci. U.S.A. 85:1883-1887 (1988) .

Background Reference 04

Kim J.W., et al.Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.

Other Product Names

Beta-hexosaminidase subunit beta, 3.2.1.52, Beta-N-acetylhexosaminidase subunit beta, Hexosaminidase subunit B, Cervical cancer proto-oncogene 7 protein, HCC-7, N-acetyl-beta-glucosaminidase subunit beta, Beta-hexosaminidase subunit beta chain B, Beta-hexosaminidase subunit beta chain A, HEXB